Head to Head
| Uruguay Clausura | 2017/11/05 22:00 | Penarol v Defensor Sporting | W | 3-1 |
| Uruguay Torneo Intermedio | 2017/07/08 19:00 | Penarol v Defensor Sporting | L | 2-3 |
| Uruguay Apertura | 2017/03/25 19:30 | Defensor Sporting v Penarol | D | 2-2 |
| Uruguay Apertura | 2016/12/10 20:15 | Penarol v Defensor Sporting | L | 0-2 |
| Uruguay Clausura | 2016/02/21 23:00 | Penarol v Defensor Sporting | W | 5-1 |
| Uruguay Apertura | 2015/08/30 21:00 | Defensor Sporting v Penarol | L | 3-1 |
| Uruguay Clausura | 2015/03/15 20:00 | Penarol v Defensor Sporting | W | 2-0 |
| Uruguay Apertura | 2014/09/06 18:00 | Defensor Sporting v Penarol | D | 0-0 |
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